Medicine Reaction, Leg Problems

Some medicines can cause leg problems. A few examples are:

• Birth control pills and estrogen. These can increase the risk of blood clots in the leg, which may cause pain or swelling.
• Calcium channel blockers, which are used to treat high blood pressure. These can cause leg swelling.
• Diuretics. These can cause leg cramps.
• Fluoroquinolones. These can increase the risk for tendinitis or tendon rupture.